RELN antibody

• Background :

  Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity) .

• Synonyms :

  Reelin|RELN

• Gene ID :

  5649

• UniProt :

  P78509

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Reelin

• Target :

  RELN

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC

• Field of Research :

  Neuroscience, Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  62 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC