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RAPSN antibody

CAT: 0710-FNab07118Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07118Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
43 kDa receptor-associated protein of the synapse (RAPsyn) |43 kDa postsynaptic protein|Acetylcholine receptor-associated 43 kDa protein|RING finger protein 205|RAPSN|RNF205
Gene ID
5913
UniProt
Q13702
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Receptor-associated protein of the synapse
Target
RAPSN
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC