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PTPN14 antibody

CAT: 0710-FNab06933Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06933Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.
Synonyms
Tyrosine-protein phosphatase non-receptor type 14|Protein-tyrosine phosphatase pez|PTPN14|PEZ|PTPD2
Gene ID
5784
UniProt
Q15678
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein tyrosine phosphatase, non-receptor type 14
Target
PTPN14
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
150 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q15678

Tyrosine-protein phosphatase non-receptor type 14

PTN14_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15678
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PTPN14
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.48
Processing
—
Secondary accessions
Q5VSI0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

CytoplasmCytoskeletonNucleus

Molecular function

HydrolaseProtein phosphatase

PTM

PhosphoproteinUbl conjugation

Biological process

TranscriptionTranscription regulation

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