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PTGES3 antibody

CAT: 0710-FNab06918Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06918Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363) . Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419) . Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448) .
Synonyms
Prostaglandin E synthase 3|Cytosolic prostaglandin E2 synthase (cPGES) |Hsp90 co-chaperone|Progesterone receptor complex p23|Telomerase-binding protein p23|PTGES3|P23|TEBP
Gene ID
10728
UniProt
Q15185
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Prostaglandin E synthase 3 (cytosolic)
Target
PTGES3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF, IP, WB, FC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21-23 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF, IP, WB, FC

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