PTGS2 antibody

• Background:

  Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

• Synonyms:

  Prostaglandin G/H synthase 2|Cyclooxygenase-2 (COX-2) |PHS II|Prostaglandin H2 synthase 2 (PGH synthase 2, PGHS-2) |Prostaglandin-endoperoxide synthase 2|PTGS2|COX2

• Gene ID:

  5743

• UniProt:

  P35354

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

• Target:

  PTGS2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Cancer, Cardiovascular, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  64 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF

• Immunogen Sequence:

  18-110aa