PPARD antibody

• Background:

  Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.

• Synonyms:

  Peroxisome proliferator-activated receptor delta (PPAR-delta) |NUCI|Nuclear hormone receptor 1 (NUC1) |Nuclear receptor subfamily 1 group C member 2|Peroxisome proliferator-activated receptor beta (PPAR-beta) |PPARD|NR1C2|PPARB

• Gene ID:

  5467

• UniProt:

  Q03181

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Peroxisome proliferator-activated receptor delta

• Target:

  PPARD

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Signal Transduction, Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:1000; IHC: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  50 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC