PPARG antibody

• Background:

  This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

• Synonyms:

  Peroxisome proliferator-activated receptor gamma (PPAR-gamma) |Nuclear receptor subfamily 1 group C member 3|PPARG|NR1C3

• Gene ID:

  5468

• UniProt:

  P37231

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Peroxisome proliferator-activated receptor gamma

• Target:

  PPARG

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF, IHC, IP

• Field of Research:

  Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience, Stem Cells

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100; IP: 1:500-1:1000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  58 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF, IHC, IP