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POLR1E antibody

CAT: 0710-FNab06619Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06619Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (By similarity) .
Synonyms
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) |DNA-directed RNA polymerase I subunit E|RNA polymerase I-associated factor 1|RNA polymerase I-associated factor 53|POLR1E|PAF53|PRAF1
Gene ID
64425
UniProt
Q9GZS1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Polymerase (RNA) I polypeptide E, 53kDa
Target
POLR1E
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
47-53 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

UniProtKB · Q9GZS1

DNA-directed RNA polymerase I subunit RPA49

RPA49_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9GZS1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POLR1E
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
RNA polymerase I subunit A49
EC number
—
Processing
—
Secondary accessions
Q5VZT3, Q8NBA9, Q96L20
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

DNA-directed RNA polymeraseNucleus

Biological process

Transcription

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