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PLEKHF1 antibody

CAT: 0710-FNab06540Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06540Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Synonyms
Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1) |Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains (Apoptosis-inducing protein) |PH and FYVE domain-containing protein 1|Phafin-1|Zinc finger FYVE domain-containing protein 15|PLEKHF1|APPD|LAPF|ZFYVE15
Gene ID
79156
UniProt
Q96S99
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Pleckstrin homology domain containing, family F (with FYVE domain) member 1
Target
PLEKHF1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
31 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC