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PLEKHA8 antibody

CAT: 0710-FNab06537Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06537Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
Synonyms
Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) |Phosphatidylinositol-four-phosphate adapter protein 2 (FAPP-2, Phosphoinositol 4-phosphate adapter protein 2, hFAPP2) |Serologically defined breast cancer antigen NY-BR-86|PLEKHA8|FAPP2
Gene ID
84725
UniProt
Q96JA3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Target
PLEKHA8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
49 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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