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NUDT11 antibody

CAT: 0710-FNab05899Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05899Size:100 µg
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Background
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Synonyms
Diphosphoinositol polyphosphate phosphohydrolase 3-beta (DIPP-3-beta, DIPP3-beta, hDIPP3beta) |Diadenosine 5',5'''-P1, P6-hexaphosphate hydrolase 3-beta|Diadenosine hexaphosphate hydrolase (AMP-forming) |Nucleoside diphosphate-linked moiety X motif 11 (Nudix motif 11) |hAps1|NUDT11|APS1|DIPP3B
Gene ID
55190
UniProt
Q96G61
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Nudix (nucleoside diphosphate linked moiety X) -type motif 11
Target
NUDT11
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
19 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
1-164aa

UniProtKB · Q96G61

Diphosphoinositol polyphosphate phosphohydrolase 3-beta

NUD11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96G61
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NUDT11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
DIPP-3-beta, DIPP3-beta, hDIPP3beta
EC number
3.6.1.52
Processing
—
Secondary accessions
Q9NVN0
Protein keywords

Cellular component

Cytoplasm

Molecular function

Hydrolase

Ligand

MagnesiumManganeseMetal-binding

Technical term

Reference proteome

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