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NUDT3 antibody

CAT: 0710-FNab05905Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05905Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Synonyms
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) |Diadenosine hexaphosphate hydrolase (Ap6A hydrolase) |Endopolyphosphatase|Nucleoside diphosphate-linked moiety X motif 3 (Nudix motif 3) |m7GpppN-mRNA hydrolase|m7GpppX diphosphatase|NUDT3|DIPP|DIPP1
Gene ID
11165
UniProt
O95989
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Nudix (nucleoside diphosphate linked moiety X) -type motif 3
Target
NUDT3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
20-30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB