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IQCB1 antibody

CAT: 0710-FNab05818Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05818Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.
Synonyms
IQ calmodulin-binding motif-containing protein 1|Nephrocystin-5|p53 and DNA damage-regulated IQ motif protein (PIQ) |IQCB1|KIAA0036|NPHP5
UniProt
Q15051
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
IQ motif containing B1
Target
IQCB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF
Field of Research
Epigenetics, Signal Transduction
Purification
Immunogen affinity purified
Dilution
IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF

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