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NKX2-5 antibody

CAT: 0710-FNab05751Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05751Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity) . It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity) . It is required for spleen development.
Synonyms
Homeobox protein Nkx-2.5|Cardiac-specific homeobox|Homeobox protein CSX|Homeobox protein NK-2 homolog E|NKX2-5|CSX|NKX2.5|NKX2E
Gene ID
1482
UniProt
P52952
Host
Rabbit
Reactivity
Human
Immunogen
NK2 transcription factor related, locus 5 (Drosophila)
Target
NKX2-5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Metabolism, Cardiovascular, Developmental biology, Neuroscience, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
37 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P52952

Homeobox protein Nkx-2.5

NKX25_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P52952
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NKX2-5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K3K0, B4DNB6, E9PBU6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Atrial septal defectCongenital hypothyroidismDisease variant

Molecular function

Developmental proteinDNA-binding

Domain

Homeobox

Cellular component

Nucleus

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Alternative Products

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GTR17691229Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody
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GTR18542099Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (Cy3)
GTR18542095Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (PE)
GTR18726510Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (Fluoro550)
GTR18726508Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (Fluoro647)
GTR18542097Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (HRP)
GTR18542096Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (APC)
GTR18726511Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (Fluoro488)
GTR18726509Nkx2.5/NKX2-5/NKX2 Rabbit Polyclonal Antibody (Fluoro594)

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