Products for Research Use Only
RegisterLogin

IGKV1-5 antibody

CAT: 0710-FNab04188Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab04188Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
V segment of the variable domain of immunoglobulins light chain that participates to the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414) . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V- (D) -J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170) .
Synonyms
Immunoglobulin kappa variable 1-5|Ig kappa chain V-I region CAR|Ig kappa chain V-I region EU|Ig kappa chain V-I region HK102|Ig kappa chain V-I region Kue|IGKV1-5
UniProt
P01602
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Immunoglobulin kappa variable 1-5
Target
IGKV1-5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P01602

Immunoglobulin kappa variable 1-5

KV105_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01602
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IGKV1-5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A0A075B6S8, P01596, P01598, P01604
Protein keywords

Biological process

Adaptive immunityImmunity

Cellular component

Cell membraneImmunoglobulinMembraneSecreted

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bond

Domain

Immunoglobulin domainSignal

Related Products

CatalogName
FNab05751NKX2-5 antibody
FNab099285-HT antibody
FNab109035-FAM antibody
PCP55-30238-01PerCP-Cy5.5 Anti-Human CD38 Antibody (AT13/5)
PCP55-30038-01PerCP-Cy5.5 Anti-Human CD40 Antibody (G28.5)
PCP55-30128-01PerCP-Cy5.5 Anti-Mouse CD4 Antibody (RM4-5)
P55-30001-01PE-Cy5.5 Anti-Mouse CD4 Antibody (GK1.5)
PCP55-30128U-01PerCP-Cy5.5 Anti-Mouse CD4 Antibody (RM4-5)
PC55-30001U-01PerCP-Cy5.5 Anti-Mouse CD4 Antibody (GK1.5)
P55-30001U-01PE-Cy5.5 Anti-Mouse CD4 Antibody (GK1.5)

Alternative Products

CatalogName
CSB-PA011359GA01HUIGKV1-5 Antibody
GTR18202034IGKV1-5 Polyclonal Antibody
PAab04188Anti-IGKV1-5 antibody
H00028299-B01PMouse Polyclonal IGKV1-5 Antibody
GTR19001549IGKV1-5 Antibody Blocking Peptide
GTR17706681-01IGKV1-5 Rabbit Polyclonal Antibody
SL18139R-01Rabbit Anti-IGKV1-5 antibody
GTR18034459-01IGKV1 5 Rabbit Polyclonal Antibody
GTR17846957IGKV1-5 Rabbit Polyclonal Antibody (Cy5.5)
GTR17716338IGKV1-5 Rabbit Polyclonal Antibody (HRP)

Popular Products