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NCOA3 antibody

CAT: 0710-FNab05589Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05589Size:100 µg
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Background
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs) . Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
Synonyms
Nuclear receptor coactivator 3 (NCoA-3) |ACTR|Amplified in breast cancer 1 protein (AIB-1) |CBP-interacting protein (pCIP) |Class E basic helix-loop-helix protein 42 (bHLHe42) |Receptor-associated coactivator 3 (RAC-3) |Steroid receptor coactivator protein 3 (SRC-3) |Thyroid hormone receptor activator molecule 1 (TRAM-1) |NCOA3|AIB1|BHLHE42|RAC3|TRAM1
Gene ID
8202
UniProt
Q9Y6Q9
Host
Rabbit
Reactivity
Human
Immunogen
Nuclear receptor coactivator 3
Target
NCOA3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC, FC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
160 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC, FC

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