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MZB1 antibody

CAT: 0710-FNab05530Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05530Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity) . Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca (2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
Synonyms
Marginal zone B- and B1-cell-specific protein|Mesenteric estrogen-dependent adipose 7 (MEDA-7) |Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein, pERp1) |Proapoptotic caspase adapter protein|MZB1|MEDA7|PACAP
Gene ID
51237
UniProt
Q8WU39
Host
Rabbit
Reactivity
Human
Immunogen
Hypothetical protein MGC29506
Target
MZB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC