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MYH9 antibody

CAT: 0710-FNab05481Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05481Size:100 µg
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Background
During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (By similarity) . Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.
Synonyms
Myosin-9|Cellular myosin heavy chain, type A|Myosin heavy chain 9|Myosin heavy chain, non-muscle IIa|Non-muscle myosin heavy chain A (NMMHC-A) |Non-muscle myosin heavy chain IIa (NMMHC II-a, NMMHC-IIA) |MYH9
Gene ID
17886
UniProt
P35579
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Myosin, heavy polypeptide 9, non-muscle
Target
MYH9
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Immunology, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
224 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

UniProtKB · P35579

Myosin-9

MYH9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35579
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYH9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K6E4, O60805, Q60FE2, Q86T83
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoproteinUbl conjugation

Molecular function

Actin-bindingCalmodulin-bindingHost cell receptor for virus entryMotor proteinMyosinReceptor

Disease

Alport syndromeCataractDeafnessDisease variantNon-syndromic deafness

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell adhesionCell shape

Cellular component

Cell membraneCytoplasmCytoplasmic vesicleCytoskeletonMembrane

Domain

Coiled coil

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