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MYH1 antibody

CAT: 0710-FNab05469Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05469Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development.
Synonyms
Myosin-1|Myosin heavy chain 1|Myosin heavy chain 2x (MyHC-2x) |Myosin heavy chain IIx/d (MyHC-IIx/d) |Myosin heavy chain, skeletal muscle, adult 1|MYH1
Gene ID
4619
UniProt
P12882
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Myosin, heavy chain 1, skeletal muscle, adult
Target
MYH1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cancer, Immunology, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
260 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
449-651aa

UniProtKB · P12882

Myosin-1

MYH1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12882
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q14CA4, Q9Y622
Protein keywords

Molecular function

Actin-bindingCalmodulin-bindingMotor proteinMuscle proteinMyosin

Ligand

ATP-bindingNucleotide-binding

Domain

Coiled coil

Cellular component

CytoplasmThick filament

Biological process

Hearing

PTM

MethylationPhosphoprotein

Technical term

Proteomics identificationReference proteome

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