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MMP13 antibody

CAT: 0710-FNab05235Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05235Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.It can detect the glycosylated proMMP-13 (70 kDa), unglycosylated proform (54 kDa) .
Synonyms
Collagenase 3|Matrix metalloproteinase-13 (MMP-13) |MMP13
Gene ID
4322
UniProt
P45452
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Matrix metallopeptidase 13 (collagenase 3)
Target
MMP13
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Stem Cells, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
54 kDa, 70 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF

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