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MEX3C antibody

CAT: 0710-FNab05145Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05145Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
Synonyms
RNA-binding E3 ubiquitin-protein ligase MEX3C|RING finger and KH domain-containing protein 2|RING finger protein 194|RING-type E3 ubiquitin transferase MEX3C|MEX3C|RKHD2|RNF194
Gene ID
51320
UniProt
Q5U5Q3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Mex-3 homolog C (C. elegans)
Target
MEX3C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
69 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC