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MBNL3 antibody

CAT: 0710-FNab05041Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05041Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM) . Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
Synonyms
Muscleblind-like protein 3|Cys3His CCG1-required protein|Muscleblind-like X-linked protein|Protein HCHCR|MBNL3|CHCR|MBLX39|MBXL
Gene ID
55796
UniProt
Q9NUK0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Muscleblind-like 3 (Drosophila)
Target
MBNL3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
38 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

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