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MARCHF8 antibody

CAT: 0710-FNab05004Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05004Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
Synonyms
E3 ubiquitin-protein ligase MARCHF8|Cellular modulator of immune recognition (c-MIR) |Membrane-associated RING finger protein 8|Membrane-associated RING-CH protein VIII (MARCH-VIII) |RING finger protein 178|RING-type E3 ubiquitin transferase MARCHF8|MARCHF8|MARCH8|MIR|RNF178
Gene ID
220972
UniProt
Q5T0T0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Membrane-associated ring finger (C3HC4) 8
Target
MARCHF8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP