MARCHF5 antibody

• Background:

  Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1.

• Synonyms:

  E3 ubiquitin-protein ligase MARCHF5|Membrane-associated RING finger protein 5|Membrane-associated RING-CH protein V (MARCH-V) |Mitochondrial ubiquitin ligase (MITOL) |RING finger protein 153|RING-type E3 ubiquitin transferase MARCHF5|MARCHF5|MARCH5|RNF153

• Gene ID:

  54708

• UniProt:

  Q9NX47

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Membrane-associated ring finger (C3HC4) 5

• Target:

  MARCHF5

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  31 kDa/65-70 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC