MAD2L1 antibody

• Background:

  Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

• Synonyms:

  Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) |Mitotic arrest deficient 2-like protein 1 (MAD2-like protein 1) |MAD2L1|MAD2

• Gene ID:

  4085

• UniProt:

  Q13257

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  MAD2 mitotic arrest deficient-like 1 (yeast)

• Target:

  MAD2L1

• Clonality:

  Monoclonal

• Isotype:

  IgG2a

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Cell Division and Proliferation

• Purification:

  Protein A+G purification

• Dilution:

  WB: 1:1000-1:3000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  25-30 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  8G6

• Tested Applications:

  ELISA, WB, IHC