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IFNGR2 antibody

CAT: 0710-FNab04150Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04150Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:8124716, PubMed:7673114, PubMed:7615558) . Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:8124716, PubMed:7673114, PubMed:15356148) . Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114) .
Synonyms
Interferon gamma receptor 2 (IFN-gamma receptor 2, IFN-gamma-R2) |Interferon gamma receptor accessory factor 1 (AF-1) |Interferon gamma receptor beta-chain (IFN-gamma-R-beta) |Interferon gamma transducer 1|IFNGR2|IFNGT1
Gene ID
3460
UniProt
P38484
Host
Rabbit
Reactivity
Human
Immunogen
Interferon gamma receptor 2 (interferon gamma transducer 1)
Target
IFNGR2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P38484

Interferon gamma receptor 2

INGR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P38484
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNGR2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IFN-gamma receptor 2, IFN-gamma-R2
EC number
—
Processing
Precursor
Secondary accessions
Q9BTL5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneCytoplasmCytoplasmic vesicleEndoplasmic reticulumGolgi apparatusMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix

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