IFNG antibody

CAT: 0710-FNab04358Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab04358Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Interferon gamma (IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB) . Mutations in this gene are associated with aplastic anemia.

Synonyms

Interferon gamma (IFN-gamma) |Immune interferon|IFNG

Gene ID

3458

UniProt

P01579

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Interferon, gamma

Target

IFNG

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, WB

Field of Research

Immunology, Cardiovascular, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

19 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC, WB

Immunogen Sequence

22-166aa

UniProtKB · P01579

Interferon gamma

IFNG_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P01579
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: IFNG
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: IFN-gamma
EC number: —
Processing: Precursor
Secondary accessions: B5BU88, Q53ZV4

Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Antiviral defenseGrowth regulation

PTM

Cleavage on pair of basic residuesGlycoproteinPyrrolidone carboxylic acid

Molecular function

Cytokine

Cellular component

Secreted

Domain

Signal

Related Products

Catalog	Name
P0148-01	Recombinant Canine IFNG
P0146-01	Recombinant Bovine IFNG
P0152-01	Recombinant Rat IFNG
Pr10141-01	Recombinant Mouse IFNG
P0147-01	Recombinant Chicken IFNG
P0150-01	Recombinant Mouse IFNG
Pr10193-01	Recombinant Human IFNG
P9969-01	Recombinant Monkey IFNG
P5794-01	Recombinant Human IFNG
P1391-01	Recombinant Hamster IFNG

Alternative Products

Catalog	Name
GTR17982394	IFNG Antibody