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IFIT5 antibody

CAT: 0710-FNab04139Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04139Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.
Synonyms
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) |Interferon-induced 58 kDa protein|Retinoic acid- and interferon-inducible 58 kDa protein (P58) |IFIT5|ISG58|RI58
Gene ID
24138
UniProt
Q13325
Host
Rabbit
Reactivity
Human
Immunogen
Interferon-induced protein with tetratricopeptide repeats 5
Target
IFIT5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56-58 kDa, 48 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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