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ICOS antibody

CAT: 0710-FNab04110Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04110Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity) .
Synonyms
Inducible T-cell costimulator|Activation-inducible lymphocyte immunomediatory molecule|ICOS|AILIM
Gene ID
29851
UniProt
Q9Y6W8
Host
Rabbit
Reactivity
Human
Immunogen
Inducible T-cell co-stimulator
Target
ICOS
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cancer, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
28 kDa, 45-50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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