HDAC3 antibody

CAT: 0710-FNab03798Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab03798Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Synonyms
Histone deacetylase 3 (HD3) |Protein deacetylase HDAC3|Protein deacylase HDAC3|RPD3-2|SMAP45|HDAC3
Gene ID
8841
UniProt
O15379
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Histone deacetylase 3
Target
HDAC3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IP, WB, IF
Field of Research
Epigenetics, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200; IP: 1:50 - 1:200; ChIP: 1:20 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
47 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IP, WB, IF

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