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GUF1 antibody

CAT: 0710-FNab03730Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03730Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Synonyms
Translation factor GUF1, mitochondrial|Elongation factor 4 homolog (EF-4) |GTPase GUF1|Ribosomal back-translocase|GUF1
Gene ID
60558
UniProt
Q8N442
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
GUF1 GTPase homolog
Target
GUF1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC, IP
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC, IP

UniProtKB · Q8N442

Translation factor GUF1, mitochondrial

GUF1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N442
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GUF1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.5.-
Processing
Precursor
Secondary accessions
Q5XKM8, Q9H710, Q9H8U4
Protein keywords

Disease

Disease variantEpilepsy

Ligand

GTP-bindingNucleotide-binding

Molecular function

Hydrolase

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Biological process

Protein biosynthesis

Technical term

Proteomics identificationReference proteome

Domain

Transit peptide

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Alternative Products

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