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GSDMD antibody

CAT: 0710-FNab03670Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03670Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Synonyms
Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD) |Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD) |Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1
Gene ID
79792
UniProt
P57764
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Gasdermin D
Target
GSDMD
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-53 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
276-484aa

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