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Recombinant Human GSDMD

CAT: 0710-P2058-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P2058-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1
UniProt
P57764
Expression Region
276-484
Host
E.Coli
Tag
N-terminal His-IF2DI Tag
Applications
Western Blot, ELISA
Field of Research
Developmental biology
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
43.0 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · P57764

Gasdermin-D

GSDMD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P57764
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GSDMD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K702, D3DWJ9, Q96Q98
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cell membraneCytoplasmInflammasomeMembraneMitochondrionNucleusSecreted

PTM

GlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Biological process

ImmunityInflammatory responseInnate immunityNecrosisTranscriptionTranscription regulation

Ligand

Lipid-binding

Domain

TransmembraneTransmembrane beta strand

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