EXD2 antibody

• Background :

  Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

• Synonyms :

  Exonuclease 3'-5' domain-containing protein 2|3'-5' exoribonuclease EXD2|Exonuclease 3'-5' domain-like-containing protein 2|EXD2|C14orf114|EXDL2

• Gene ID :

  55218

• UniProt :

  Q9NVH0

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Exonuclease 3'-5' domain containing 2

• Target :

  EXD2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IF, IHC, IP

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  56 kDa, 70 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IF, IHC, IP

• Immunogen Sequence :

  400-621aa