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EXD1 antibody

CAT: 0710-FNab02889Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02889Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity) . The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease (By similarity) .
Synonyms
PiRNA biogenesis protein EXD1|Exonuclease 3'-5' domain-containing protein 1|Exonuclease 3'-5' domain-like-containing protein 1|Inactive exonuclease EXD1|EXD1|EXDL1
Gene ID
161829
UniProt
Q8NHP7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Exonuclease 3'-5' domain containing 1
Target
EXD1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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