EIF2S2 antibody

CAT: 0710-FNab02700Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02700Size:100 µg
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Background
EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Synonyms
Eukaryotic translation initiation factor 2 subunit 2|Eukaryotic translation initiation factor 2 subunit beta (eIF2-beta) |EIF2S2|EIF2B
Gene ID
8894
UniProt
P20042
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
Target
EIF2S2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

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