EIF4A2 antibody

• Background:

  ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

• Synonyms:

  Eukaryotic initiation factor 4A-II (eIF-4A-II, eIF4A-II) |ATP-dependent RNA helicase eIF4A-2|EIF4A2|DDX2B|EIF4F

• Gene ID:

  1974

• UniProt:

  Q14240

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Eukaryotic translation initiation factor 4A, isoform 2

• Target:

  EIF4A2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF, IHC, IP

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  47 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF, IHC, IP

• Immunogen Sequence:

  110-407aa