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DMAP1 antibody

CAT: 0710-FNab02421Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02421Size:100 µg
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Background
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Synonyms
DNA methyltransferase 1-associated protein 1 (DNMAP1, DNMT1-associated protein 1) |DMAP1|KIAA1425
Gene ID
55929
UniProt
Q9NPF5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
DNA methyltransferase 1 associated protein 1
Target
DMAP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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