DHDDS antibody

• Background :

  With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) . Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.

• Synonyms :

  Dehydrodolichyl diphosphate synthase complex subunit DHDDS|Cis-isoprenyltransferase (CIT, Cis-IPTase) |Cis-prenyltransferase subunit hCIT|Epididymis tissue protein Li 189m|DHDDS|HDS

• Gene ID :

  79947

• UniProt :

  Q86SQ9

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Dehydrodolichyl diphosphate synthase

• Target :

  DHDDS

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  34 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB