DEDD2 antibody

• Background :

  May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.

• Synonyms :

  DNA-binding death effector domain-containing protein 2|DED-containing protein FLAME-3|FADD-like anti-apoptotic molecule 3|DEDD2|FLAME3

• Gene ID :

  162989

• UniProt :

  Q8WXF8

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Death effector domain containing 2

• Target :

  DEDD2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC, WB

• Field of Research :

  Signal Transduction, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  36 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC, WB