DEDD antibody

• Background :

  A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity) .

• Synonyms :

  Death effector domain-containing protein|DEDPro1|Death effector domain-containing testicular molecule|FLDED-1|DEDD|DEDPRO1|DEFT

• Gene ID :

  9191

• UniProt :

  O75618

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Death effector domain containing

• Target :

  DEDD

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC

• Field of Research :

  Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC