DEDD antibody

• Background:

  A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity) .

• Synonyms:

  Death effector domain-containing protein|DEDPro1|Death effector domain-containing testicular molecule|FLDED-1|DEDD|DEDPRO1|DEFT

• Gene ID:

  9191

• UniProt:

  O75618

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Death effector domain containing

• Target:

  DEDD

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC

• Field of Research:

  Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC