DEDD antibody

CAT: 710-FNab02323Size: 100 µgDry Ice: NoHazardous: No
100 µgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity) .
Synonyms
Death effector domain-containing protein|DEDPro1|Death effector domain-containing testicular molecule|FLDED-1|DEDD|DEDPRO1|DEFT
Gene ID
9191
UniProt
O75618
Host
Rabbit
Reactivity
Human
Immunogen
Death effector domain containing
Target
DEDD
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC