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Collagen Type III antibody

CAT: 0710-FNab01839Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01839Size:100 µg
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Background
Type III collagen is a fibrillar forming collagen comprising three a1 (III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. It occurs in most soft connective tissues along with type I collagen. COL3A1 gene encodes type III procollagen. Mutations in this gene are associated with type III and IV Ehlers-Danlos syndrome, and with aortic and arterial aneurysms. (PMID: 9050868; 2445760)
Synonyms
Collagen alpha-1 (III) chain|COL3A1
Gene ID
1281
UniProt
P02461
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Collagen, type III, alpha 1
Target
Collagen Type III
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Stem Cells, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140-150 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
1217-1466aa

UniProtKB · P02461

Collagen alpha-1(III) chain

CO3A1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02461
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
COL3A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
D2JYH5, D3DPH4, P78429, Q15112, Q16403, Q53S91, Q541P8, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56, Q8N6U4, Q9UC88, Q9UC89, Q9UC90, Q9UC91, R4N3C5, V9GZI1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Aortic aneurysmDisease variantEhlers-Danlos syndrome

Ligand

CalciumMetal-binding

Domain

CollagenRepeatSignal

PTM

Disulfide bondGlycoproteinHydroxylation

Cellular component

Extracellular matrixSecreted

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