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CNGA3 antibody

CAT: 0710-FNab01796Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01796Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity) . Essential for the generation of light-evoked electrical responses in the red-, green-and blue sensitive cones.
Synonyms
Cyclic nucleotide-gated cation channel alpha-3|Cone photoreceptor cGMP-gated channel subunit alpha|Cyclic nucleotide-gated channel alpha-3 (CNG channel alpha-3, CNG-3, CNG3) |CNGA3|CNCG3
Gene ID
1261
UniProt
Q16281
Host
Rabbit
Reactivity
Human
Immunogen
Cyclic nucleotide gated channel alpha 3
Target
CNGA3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
98 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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