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CCNY antibody

CAT: 0710-FNab01386Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01386Size:100 µg
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Background
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Synonyms
Cyclin-Y (Cyc-Y) |Cyclin box protein 1|Cyclin fold protein 1|cyclin-X|CCNY|C10orf9|CBCP1|CFP1
Gene ID
219771
UniProt
Q8ND76
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Cyclin Y
Target
CCNY
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP
Field of Research
Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33-39 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP

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