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CACNA1G antibody

CAT: 0710-FNab01172Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01172Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA) " group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Synonyms
Voltage-dependent T-type calcium channel subunit alpha-1G|Cav3.1c|NBR13|Voltage-gated calcium channel subunit alpha Cav3.1|CACNA1G|KIAA1123
Gene ID
8913
UniProt
O43497
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Calcium channel, voltage-dependent, T type, alpha 1G subunit
Target
CACNA1G
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF

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