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BAG1S-specific antibody

CAT: 0710-FNab00788Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00788Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BAG1 have been identified that modulate gene transcription through poorly defined mechanisms. Four isoforms of the BAG1 protein (BAG1S, BAG1, BAG1M and BAG1L) can be produced from a common mRNA by use of alternative translation initiation sites, including a non-canonical CTG codon in one instance. The longest, BAG1L (Mr ~50K), contains a nuclear localization signal (NLS) and resides in the nucleus, whereas BAG1M (Mr ~46K) has an incomplete NLS and distributes mainly in cytosol, unless dragged into the nucleus through interactions with other. Distribution of BAG1S (p33) is not clear yet. This antibody recongizes all the isoforms of BAG1, includes GAG1L, BAG1V, BAG1M and BAG1S.
Synonyms
BAG family molecular chaperone regulator 1 (BAG-1) |Bcl-2-associated athanogene 1|BAG1|HAP
Gene ID
573
UniProt
Q99933
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
BCL2-associated athanogene
Target
BAG1S
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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