Prostate Specific Antibody

CAT: 0800-V7014-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V7014-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. Prostate specific antigen/KLK3 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. [RefSeq]
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P07288
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human PSA protein was used as the immunogen for the Prostate Specific antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PSAK3-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Prostate Specific antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Prostate Specific antibody is available for research use only.
Storage Conditions
Store the Prostate Specific antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
IHC testing of human prostate carcinoma with Prostate Specific antibody (clone PSAK3-1) . Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.

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