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UBASH3A-Specific antibody

CAT: 0710-FNab09150Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09150Size:100 µg
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Background
UBASH3A gene encodes ubiquitin-associated and SH3 domain-containing protein A (UBASH3A) also known as T-cell ubiquitin ligand 1 (TULA1) which is one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. UBASH3A gene expression is limited to only a few tissues, with its highest expression in spleen, peripheral blood leukocytes, and bone marrow. UBASH3A protein is associated with c-Cbl and ubiquitylated proteins and has been implicated in the regulation of signaling mediated by protein-tyrosine kinases oth family members can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells via its interaction with apoptosis-inducing factor (AIF) . This antibody is UBASH3A-specific.
Synonyms
Ubiquitin-associated and SH3 domain-containing protein A|Cbl-interacting protein 4 (CLIP4) |Suppressor of T-cell receptor signaling 2 (STS-2) |T-cell ubiquitin ligand 1 (TULA-1) |UBASH3A|STS2
Gene ID
53347
UniProt
P57075
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ubiquitin associated and SH3 domain containing, A
Target
UBASH3A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IF: 1:10-1:100; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
69 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP

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