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ARHGEF7 antibody

CAT: 0710-FNab00564Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00564Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity) . May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Synonyms
Rho guanine nucleotide exchange factor 7|Beta-Pix|COOL-1|PAK-interacting exchange factor beta|p85|ARHGEF7|COOL1|KIAA0142|P85SPR|PAK3BP|PIXB
Gene ID
8874
UniProt
Q14155
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Rho guanine nucleotide exchange factor (GEF) 7
Target
ARHGEF7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IP, WB
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IP: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IP, WB

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