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SERPINA3 antibody

CAT: 0710-FNab00317Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00317Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Synonyms
Alpha-1-antichymotrypsin (ACT) |Cell growth-inhibiting gene 24/25 protein|Serpin A3|Alpha-1-antichymotrypsin His-Pro-less|SERPINA3|AACT
Gene ID
12
UniProt
P01011
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Target
SERPINA3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Cancer, Immunology, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF
Immunogen Sequence
104-326aa

UniProtKB · P01011

Alpha-1-antichymotrypsin

AACT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01011
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERPINA3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ACT
EC number
—
Processing
Precursor
Secondary accessions
B3KVQ7, Q13703, Q2TU87, Q2TU88, Q59GP9, Q6LBY8, Q6LDT7, Q6NSC9, Q8N177, Q96DW8, Q9UC47, Q9UNU9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Acute phase

Coding sequence diversity

Alternative splicing

PTM

Glycoprotein

Molecular function

Protease inhibitorSerine protease inhibitor

Cellular component

Secreted

Domain

Signal

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